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June 18, 2013
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Displaying results 1 - 25 of 104 for drug testing. Subscribe to this search

  1. article Drug testing and state aid

    Wednesday, May 16, 2012 4:00 am

    Many states, including Arizona, have been trying to institute drug testing for individuals applying for welfare and/or unemployment benefits. Who could object to that?  Employers today commonly require drug testing for employees. Why shouldn’t the state? I personally have had to be drug tested for jobs in the past, as I am sure you have. Even though I am not now nor have I ever been a drug user, that did not matter. All employees and prospective employees had to experience the inconvenience of the drug test. This was the new normal.

  2. article Performance-diminishing drugs

    Wednesday, February 11, 2009 12:00 am

    Alex Rodriguez has it all, or so it would appear. Looks. Unmatched baseball talent. More money than anyone could need.

  3. poll Should juveniles be subjected to a blood test for drugs without a parental consent during a traffic stop?

    Thursday, May 30, 2013 10:04 am

  4. article What's Up UA? - UA Spin-Off to Test Cancer-Preventing Drug Combination

    Tuesday, April 23, 2013 9:38 am

    Cancer Prevention Pharmaceuticals, Inc., or CPP, has helped launch a phase-III clinical trial to test the efficacy of a combination drug that has shown promise of preventing colon cancer. CPP was founded in 2008 to apply decades' worth of systematic, basic research led by University of Arizona professor emeritus Eugene Gerner and former UA researcher Frank Meyskens to improve clinical practice. 

    During the trial, which is funded by the National Cancer Institute, 1,340 colon cancer survivors will receive daily treatment for three years to prevent the occurrence of colorectal cancer or high-risk polyps and compare the effects to a placebo group. 
     
    "Our long-term vision is to change the status quo from treating and managing cancer to intervening before cancer manifests and prevent it altogether," said Jeffrey Jacob, founding CEO of Cancer Prevention Pharmaceuticals. "The idea is just like in the approach to heart disease: Instead of waiting for heart attack or stroke to happen, we give patients cholesterol-lowering or blood pressure-lowering medicine to prevent those events from happening in the first place."
     
    In addition to colorectal cancer, the same treatment approach has shown promise in preventing prostate, skin and possibly other cancers as well. Colorectal cancer affects about 1 million people in the U.S., Jacob said. 
     
    "Our two-drug-combination targets different pathways that are important in cancer development," explained CPP co-founder Eugene Gerner, who retired from the department of cellular and molecular medicine in the UA College of Medicine last year. "Over years of research using cell cultures and mouse models in the lab, we have been able to systematically elucidate the molecular pathways underlying cancer formation and how to target them with those drugs."
     
    This work then was successfully translated to the clinic with the help of the NCI and various research partners.  
     
    One, Sulindac, belongs to of the class of non-steroidal anti-inflammatory drugs, with aspirin being a notable member. Sulindac targets the inflammatory pathway. The other, called Eflornithine, homes in on the  polyamine pathway. Driven by growth factors, this pathway is essential in stimulating growth and development in most living organisms.
     
    In his research, which has been continuously funded by the NCI since 1975, Gerner collaborated closely with Meyskens, who was a professor of medicine at the UA College of Medicine before he moved to University of California, Irvine. Both were members of the Arizona Cancer Center. Even as professor emeritus, Gerner still does research in his lab at the UA and is an active member of the UA's BIO5 Institute. 
     
    Gerner said his group focused on colon cancer in the 1980s because it was the one frequent type of human cancer for which a substantial amount of genetic information became available, especially with the Human Genome Project.
     
    "Our approach strictly focuses on the biological mechanisms and the genetics," Gerner said. "I came to the UA in 1974 and initially worked in cancer therapeutics. By the mid 1980s, I was discouraged by the lack of progress that was being made at the time. So we set out to understand the underlying processes that lead to cancer, such as the roles of various growth factors and cancer-promoting genes. 
     
    According to Jacob, the company's current focus is on intervening with patients facing elevated risk, including cancer survivors or individuals with a genetic predisposition, with the ultimate goal of expand the same approach to other forms of cancer and the general at-risk population. 
     
    Gerner said that many experts estimate at least 70 percent of colorectal cancer are associated with risk factors such as weight gain and a diet high in fat and beef but low in fiber. 
     
    "However, there are a substantial number of individuals who eat perfect diets and exercise, but still face a risk from mutations that arise spontaneously or they inherited," he said. 
     
    "Our drugs are targeting growth and inflammatory pathways leading to the synthesis of polyamines, but diets contain polyamines also. Our company is looking at ways to manage overall risk, including diet, genetic factors and exercise."
     
    In other clinical trials, CPP is also testing the therapy on people with known genetic predispositions to colorectal cancer such as patients with Familial Adenomatous Polyposis, a genetic disease that comes with a nearly 100 percent risk of developing colon cancer before age 40. 
     
    "The only option for most people with FAP is to remove the entire colon in their late teens or early twenties," Gerner said, "and they still face a lifetime of surgeries to control the condition."
     
    Neuroblastoma, a pediatric cancer and the second leading killer of children with cancer, according to Jacob, is another avenue the company is pursuing in a clinical trial. 
     
    In addition to drug therapies, CPP is considering partnerships with food companies to develop certain types of "functional foods" or "medical foods" that would exploit the same science to reduce cancer risk in certain demographics. The company is also developing new diagnostic approaches to identify people who are at higher risk for cancer who could ultimately benefit from specific therapies or medical foods. 
     
    "Part of our ability to reduce risk is having means to assess that risk and evaluate the effectiveness of drugs we are using," Gerner added. "For example, some drugs work better in some people than in others. The goal is to develop diagnostics that tell us about an individual's susceptibility."
     
    David Alberts, director of the UA's Arizona Cancer Center, said: "Gene Gerner and Frank Meyskens, both absolutely brilliant scientists, have transformed exciting laboratory research findings into medications that have the great potential of saving hundreds of thousands of lives. We are very proud that the University of Arizona Cancer Center served as the incubator for this powerful, new chemoprevention technology for colorectal cancer and treatment for recurrent neuroblastoma."
     

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  5. article Drugs found in town's water supply

    Tuesday, August 26, 2008 11:00 pm

    Small amounts of drugs have been found in a well in Continental Ranch, but Tucson Water officials maintain that the levels of the pharmaceuticals are harmless.

  6. article PRESCRIPTION DRUGS FOUND IN SANTA CRUZ

    Wednesday, April 3, 2002 12:00 am

    Although experts are unsure yet if it poses a health risk, sophisticated new techniques have detected pharmaceuticals such as antibiotics, anti-inflammatory drugs, X-ray contrasting agents and antiepeleptic medication in the effluent flowing in the Santa Cruz River channel in Northwest Tucson and Marana and in nearby wells used to monitor ground water quality.

  7. article CFHS talking about drugs on campus

    Tuesday, October 18, 2005 11:00 pm

    Erin Schmidt, ESchmidt@ExplorerNews.com

  8. article Northwest, Foothills schools fight drug abuse

    Wednesday, May 31, 2006 11:00 pm

    May 31, 2006 - As drug use in public high schools continues to increase across the country, Catalina Foothills High School is hoping to stop the abuse among its teens by drug testing students next year.

  9. article The Doctor Is In - Preventing cancer starts with the annual Pap test

    Wednesday, May 2, 2012 4:00 am

    For busy women who typically put others’ needs before their own, remember that taking time to care for themselves is important to good health. Regular well-woman exams are a simple and effective way to start.

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  10. article Make Sure You Dispose of Unused Prescription Drugs Properly

    Sunday, April 7, 2013 10:00 pm

    (StatePoint) What do you do with your unused prescription pills and over-the-counter medications? Do you throw them away? Flush them down the toilet? Simply leave them in your cabinet for a rainy day?

    1 image

  11. article Doctors Can Now Test How Well Your Medicine Works

    Thursday, January 31, 2013 4:44 am

    (NAPSI)—An apple a day keeps the doctor away? Research shows an aspirin a day may do the same. How often have you heard about chewing an aspirin if you feel the symptoms of a heart attack? If it’s that critical to get the medication to your system, isn’t it as important to know you are taking a safe dose? Good news—there is a simple blood test that is available to aid your doctor in assessing response to aspirin.

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  12. article Advanced Lab Technique May Expedite Rape Kit Testing

    Thursday, December 20, 2012 3:28 pm

    (NewsUSA) - Thanks to the outrage of one tenacious Detroit prosecutor, 21 serial rapists were identified -- rapists whose DNA sat untested in a police warehouse for years. Prosecutor Kym Worthy shined an unforgiving light on the gratuitously inefficient process of testing rape kits, in fact she's pronounced a national pandemic.

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  13. article A test of life: Runner rebuilding life in Oro Valley while fighting doping allegations

    Monday, November 28, 2005 12:00 am

    CWuensch@ExplorerNews.com

  14. article Police reports

    Tuesday, September 28, 2010 11:00 pm

    On Monday, Sept. 20, at about 8:30 p.m., Oro Valley police responded to the Taco Bell near Oracle and Magee roads because two people had locked themselves in the men's restroom for about an hour and would not come out. When police arrived, the officer pounded on the door, at which time he heard the toilet flush and some coins fall on the floor. After almost a minute, two subjects, a male, 19, and a female, 17, came out of the bathroom. The man told police he and his girlfriend were taking a pregnancy test, talking, and erasing text messages on her cell phone. He told police the pregnancy test was thrown away in the trash can, which later police could not find. Police noticed the male subject appeared to be dazed about what was going on. When asked if he had done any drugs that day, he said no. When asked if he had anything illegal on him, he said he had some marijuana in his pocket. He was arrested and upon further searching, police found burnt and clean aluminum foil, a burned straw, several lighters, a knife and an electronic scale, which all are commonly used to smoke heroin. He was arrested for possession of marijuana and drug paraphernalia. The female told police she had not done any drugs and police did not find any drugs on her person. Both were released from the scene and told they would be cited for trespassing if they returned to the Taco Bell.

  15. article Pima County partners in prescription discount card program

    Wednesday, March 20, 2013 10:16 am

    Pima County is sponsoring a discount prescription card designed to provide families and individuals with significant savings on prescription drug costs.

  16. article Be Cyber Safe And Counterfeit Free

    Thursday, February 7, 2013 4:44 am

    (NAPSI)—If you’re like nearly 85 percent of Americans, you’ve bought something online.

    1 image

  17. article Prop 203 'bad medicine' for Arizona

    Tuesday, October 12, 2010 11:00 pm

    The article on "medical pot" in the Sept. 22 Explorer failed to inform its readers of several key provisions of Prop 203.

  18. article Save Yourself From Suspicious Supplements

    Thursday, February 28, 2013 4:44 am

    (NAPSI)—Protecting your health is important to everyone. That’s why the Food and Drug Administration (FDA) wants you to know that there are many dangerous products unlawfully marketed as “dietary supplements” that contain hidden drugs and chemicals. These products are sold for all sorts of conditions including weight loss, sexual enhancement, bodybuilding, arthritis and diabetes. They can contain hidden prescription ingredients at levels much higher than those found in approved drugs.

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  19. article Group collecting signatures to put measure on ballot that would legalize marijuana

    Wednesday, June 12, 2013 4:22 pm

    PHOENIX -- Voters who have seen how medical marijuana works in Arizona may get a chance to extend the ability to use the drug to all other adults.

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  20. article Pinal assessor arrested for DUI

    Wednesday, February 9, 2011 6:00 am

    Pinal County Sheriff’s deputies on Monday, Feb. 7, arrested Lewis Paul Larkin, better known as the Pinal County assessor, on charges of driving under the influence. 

  21. article Police reports

    Tuesday, May 25, 2010 11:00 pm

    On Thursday May 20, Oro Valley police responded to Wilson K-8 School in reference to a sixth-grade student in possession of marijuana. When police arrived, they were escorted to the assistant principal's office where the student was located. According the police report, a teacher and several other students reported that the student had marijuana with him and was showing it to his classmates. After a search of the bag, the assistant principal found a sunglasses case with a plastic bag inside of it containing marijuana. The student said he got it from a friend who did not go to the school, but knew it was marijuana. When the student's mother arrived, he admitted to smoking marijuana in the past but would pass a drug test. The student later changed his story saying he might not pass a drug test because he has been to parties where people were smoking marijuana. Police advised the mother that her son be drug tested. He was arrested for possession of marijuana in a drug free school zone.

  22. article Students safe on buses, officials say

    Thursday, March 17, 2005 12:00 am

    March 9, 2005 - After a school bus driver received a DUI charge while driving a bus full of students, local officials want to reassure the public that their children are safe on district buses.

  23. article Police reports

    Tuesday, July 8, 2008 11:00 pm

    A roundup of recent police activities throughout the Northwest.

  24. article Police Beat

    Wednesday, October 3, 2012 4:00 am

    Oro Valley

  25. article NWFD CHIEF, UNION AT ODDS OVER FIRING

    Tuesday, July 31, 2001 11:00 pm

    The firing of a paramedic who tested positive for cocaine use during a drug test has placed Northwest Fire and Rescue District Chief Jeff Piechura at odds with the firefighter's union that has staunchly supported him in the past.

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