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May 22, 2013
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      Oro Valley Councilman Mike Zinkin is looking to clear his name after comments made earlier this month by Mayor Satish Hiremath regarding the c…

      • posted: May 22
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Displaying results 1 - 25 of 172 for fiber. Subscribe to this search

  1. article Help your pet shed unhealthy weight

    Wednesday, May 15, 2013 10:00 pm

    (BPT) - Are you killing your pet with kindness? We’re not talking about the compassion that motivates us to vaccinate our pets, or keep them warm in cold weather. Kindness that can be harmful to pets comes in the form of an overabundance of food and treats. The all-too-common result is a pet that becomes overweight or even obese.

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  2. article Add fresh grapes for great summer dishes

    Tuesday, May 14, 2013 10:00 pm

    (BPT) - Grapes from California are in abundant supply throughout the summer, which is welcome news for those seeking a healthy, refreshing snack. They’re also a boon to the home cook: grapes provide bright color, a sweet-tart flavor and a refreshing burst of juice to warm-weather dishes.

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  3. article Re-siding 101: What To Consider, Start To Finish

    Thursday, May 9, 2013 4:44 am

    (NAPSI)—Deciding to re-side your home isn’t a small undertaking but it doesn’t have to be intimidating. You need a keen eye, some research and a game plan. Here are hints that can help:

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  4. article Bedding: A Big Choice For Small Pets

    Thursday, May 9, 2013 4:44 am

    (NAPSI)—The next time you consider expanding your family to include a hamster, Guinea pig, bunny or other small pet, you won’t be alone. Some 16 million U.S. families currently co-habitate with small pets, according to the American Pet Products Association National Pet Owners Survey.

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  5. article Tips for Choosing Carpeting for Your Home

    Wednesday, May 8, 2013 10:00 pm

    (StatePoint) Is updating your flooring on your home improvement to-do list this season? From color to style to performance, there’s a lot to consider. Learn how to find flooring that fits your lifestyle and reflects your family’s personality.

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  6. article Low-maintenance exterior upgrades that add value and style to your home

    Sunday, May 5, 2013 10:00 pm

    (BPT) - Sunny days and clear skies are perfect for making exterior home improvements. Homeowners want to use their time and money wisely, so it’s important to choose projects that are low-maintenance and have a good return on investment. 

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  7. article Warm-weather entertaining made easy with expert tips and recipes

    Wednesday, May 1, 2013 10:00 pm

    (BPT) - Warmer temperatures often mean a busier social calendar. So whether you’re planning a meal to enjoy al fresco, or whipping up a sweet treat for a neighborhood block party, it’s a great time of year to experiment in the kitchen.

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  8. article Three home improvement tips to help you breathe easier

    Wednesday, May 1, 2013 10:00 pm

    (BPT) - One in five Americans suffer from allergies, according to the Asthma and Allergy Foundation of America (AAFA). As the 2013 allergy season begins, experts warn that it may be one of the worst in recent years, with people experiencing an unusually strong reaction due to increased tree pollen.

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  9. article Simple steps to a healthier heart

    Tuesday, April 30, 2013 10:00 pm

    (BPT) - For millions of Americans, the battle against heart disease and other cardiovascular conditions goes on year round. About 600,000 people die from heart disease in the United States each year, according to the Centers for Disease Control and Prevention, making heart disease the leading cause of death for both men and women.

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  10. article A year-end report card on school cafeterias: Did they make the grade for improved nutrition?

    Thursday, April 25, 2013 10:00 am

    (BPT) - The 2012-2013 school year brought a new curriculum to school cafeterias across the United States. For most of the country’s 17,000 school districts, it was an accelerated class, requiring the complete revision of school menus, from ingredients to food pairings to recipes, to meet the new USDA nutrition guidelines.    

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  11. article Protecting and prolonging the life of your leather investment

    Thursday, April 25, 2013 10:00 am

    Mother Nature isn’t always kind to your leather goods. Dirt, salt, dry air and other harsh winter elements can damage leather if they’re left to set in for months on end. Summer days mean more exposure to damaging UV rays, so it’s important to protect all leather, including car seats, from the harsh rays of the summer sun. Leather items are assumed to be durable and thus overlooked during spring cleaning, but without proper care, leather can become faded, cracked or dried out and even too stiff to wear.

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  12. article To Mom With Love

    Thursday, April 25, 2013 4:44 am

    (NAPSI)—Show your love for mom by looking after her health with the gift of heart-smart cooking.

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  13. article What's Up UA? - UA Spin-Off to Test Cancer-Preventing Drug Combination

    Tuesday, April 23, 2013 9:38 am

    Cancer Prevention Pharmaceuticals, Inc., or CPP, has helped launch a phase-III clinical trial to test the efficacy of a combination drug that has shown promise of preventing colon cancer. CPP was founded in 2008 to apply decades' worth of systematic, basic research led by University of Arizona professor emeritus Eugene Gerner and former UA researcher Frank Meyskens to improve clinical practice. 

    During the trial, which is funded by the National Cancer Institute, 1,340 colon cancer survivors will receive daily treatment for three years to prevent the occurrence of colorectal cancer or high-risk polyps and compare the effects to a placebo group. 
     
    "Our long-term vision is to change the status quo from treating and managing cancer to intervening before cancer manifests and prevent it altogether," said Jeffrey Jacob, founding CEO of Cancer Prevention Pharmaceuticals. "The idea is just like in the approach to heart disease: Instead of waiting for heart attack or stroke to happen, we give patients cholesterol-lowering or blood pressure-lowering medicine to prevent those events from happening in the first place."
     
    In addition to colorectal cancer, the same treatment approach has shown promise in preventing prostate, skin and possibly other cancers as well. Colorectal cancer affects about 1 million people in the U.S., Jacob said. 
     
    "Our two-drug-combination targets different pathways that are important in cancer development," explained CPP co-founder Eugene Gerner, who retired from the department of cellular and molecular medicine in the UA College of Medicine last year. "Over years of research using cell cultures and mouse models in the lab, we have been able to systematically elucidate the molecular pathways underlying cancer formation and how to target them with those drugs."
     
    This work then was successfully translated to the clinic with the help of the NCI and various research partners.  
     
    One, Sulindac, belongs to of the class of non-steroidal anti-inflammatory drugs, with aspirin being a notable member. Sulindac targets the inflammatory pathway. The other, called Eflornithine, homes in on the  polyamine pathway. Driven by growth factors, this pathway is essential in stimulating growth and development in most living organisms.
     
    In his research, which has been continuously funded by the NCI since 1975, Gerner collaborated closely with Meyskens, who was a professor of medicine at the UA College of Medicine before he moved to University of California, Irvine. Both were members of the Arizona Cancer Center. Even as professor emeritus, Gerner still does research in his lab at the UA and is an active member of the UA's BIO5 Institute. 
     
    Gerner said his group focused on colon cancer in the 1980s because it was the one frequent type of human cancer for which a substantial amount of genetic information became available, especially with the Human Genome Project.
     
    "Our approach strictly focuses on the biological mechanisms and the genetics," Gerner said. "I came to the UA in 1974 and initially worked in cancer therapeutics. By the mid 1980s, I was discouraged by the lack of progress that was being made at the time. So we set out to understand the underlying processes that lead to cancer, such as the roles of various growth factors and cancer-promoting genes. 
     
    According to Jacob, the company's current focus is on intervening with patients facing elevated risk, including cancer survivors or individuals with a genetic predisposition, with the ultimate goal of expand the same approach to other forms of cancer and the general at-risk population. 
     
    Gerner said that many experts estimate at least 70 percent of colorectal cancer are associated with risk factors such as weight gain and a diet high in fat and beef but low in fiber. 
     
    "However, there are a substantial number of individuals who eat perfect diets and exercise, but still face a risk from mutations that arise spontaneously or they inherited," he said. 
     
    "Our drugs are targeting growth and inflammatory pathways leading to the synthesis of polyamines, but diets contain polyamines also. Our company is looking at ways to manage overall risk, including diet, genetic factors and exercise."
     
    In other clinical trials, CPP is also testing the therapy on people with known genetic predispositions to colorectal cancer such as patients with Familial Adenomatous Polyposis, a genetic disease that comes with a nearly 100 percent risk of developing colon cancer before age 40. 
     
    "The only option for most people with FAP is to remove the entire colon in their late teens or early twenties," Gerner said, "and they still face a lifetime of surgeries to control the condition."
     
    Neuroblastoma, a pediatric cancer and the second leading killer of children with cancer, according to Jacob, is another avenue the company is pursuing in a clinical trial. 
     
    In addition to drug therapies, CPP is considering partnerships with food companies to develop certain types of "functional foods" or "medical foods" that would exploit the same science to reduce cancer risk in certain demographics. The company is also developing new diagnostic approaches to identify people who are at higher risk for cancer who could ultimately benefit from specific therapies or medical foods. 
     
    "Part of our ability to reduce risk is having means to assess that risk and evaluate the effectiveness of drugs we are using," Gerner added. "For example, some drugs work better in some people than in others. The goal is to develop diagnostics that tell us about an individual's susceptibility."
     
    David Alberts, director of the UA's Arizona Cancer Center, said: "Gene Gerner and Frank Meyskens, both absolutely brilliant scientists, have transformed exciting laboratory research findings into medications that have the great potential of saving hundreds of thousands of lives. We are very proud that the University of Arizona Cancer Center served as the incubator for this powerful, new chemoprevention technology for colorectal cancer and treatment for recurrent neuroblastoma."
     

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  14. article Fitness tips to get ready for summer fun

    Monday, April 22, 2013 10:00 pm

    (BPT) - The sun is shining longer every day, telling you that it’s time to get ready for vacations, activities with family and friends and of course, swimsuit season. To help you prepare, there are some simple fitness tips you can follow to look and feel good this summer season.

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  15. article Improving automobile fuel efficiency - with plastics

    Sunday, April 21, 2013 10:00 pm

    While most Americans know that drastically improving automobile fuel efficiency will reduce gasoline consumption and tailpipe emissions, it may be less clear how today’s cars and trucks are evolving to make that happen.

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  16. article Healthy Flax Facts

    Thursday, April 18, 2013 4:44 am

    (NAPSI)—Adding a small seed to your diet may offer big benefits. That’s the word from experts who say that flaxseeds are an excellent way to improve your health.

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  17. article Simple tips for eating well

    Wednesday, April 17, 2013 4:00 am

    When you fuel your body each day to handle all the tasks you need to do, follow a few simple tips to optimize the nutritional value of daily intake.

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  18. article Soundproofing Tips to Turn Your Home into a Quiet Sanctuary

    Tuesday, April 16, 2013 11:18 am

    All around us, life is getting louder. But home should be a place to relax and unwind. Between televisions, cell phones, computers and video games, it’s sometimes hard to find peace and quiet within the walls of your home.

  19. article Make exterior trim part of home remodeling

    Thursday, April 11, 2013 10:00 pm

    (BPT) - As existing home sales continue to climb and housing prices increase, remodeling is also on the rise, according to the Joint Center for Housing Studies of Harvard University. Owners of older homes are investing more in home improvement projects that add beauty and value, especially with environmentally friendly products.

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  20. article Don't be Shy with Your Doctor about Gastrointestinal Symptoms

    Sunday, April 7, 2013 10:00 pm

    (StatePoint) For millions of adults in the United States, daily activities like going to work or school may also be accompanied by bothersome gastrointestinal symptoms such as abdominal pain and constipation. People may not talk to their doctor about these symptoms because they’re embarrassed and find the conversation a difficult one to have. They suffer in silence.

  21. article Soundproofing Tips to Turn Your Home into a Quiet Sanctuary

    Wednesday, April 3, 2013 10:00 pm

    (StatePoint) All around us, life is getting louder. But home should be a place to relax and unwind. Between televisions, cell phones, computers and video games, it’s sometimes hard to find peace and quiet within the walls of your home.

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  22. article Police Beat -- Week of April 1

    Wednesday, April 3, 2013 4:00 am

    Oro Valley 

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  23. article It's all in the details - how to accessorize your home exterior

    Monday, April 1, 2013 10:00 pm

    (BPT) - When considering exterior home improvements during spring and summer, many homeowners go for updates such as the replacement of siding or windows. These projects can make the home look great while boosting energy efficiency, but no matter how much homeowners invest in siding or windows, it will only look as good as the trim used to complete the job.

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  24. article How to Wash Dry-Clean-Only Clothing at Home

    Monday, April 1, 2013 9:32 am

    (NewsUSA) - When it comes to delicate fabric and dry-clean-only clothing, washing your favorite items can be quite a hassle. Picking things up from the dry cleaner isn't always a quick stop, especially if any unexplained marks or stains appear on your clothes.

    1 image

  25. pdf Saturday Crossword 3-30-13

    Saturday, March 30, 2013 12:00 am

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Sunshine School in Oro Valley read more

Sunshine School 9000 N. Oracle Road Tucson, AZ 85704, Suite 204 (520)742-6874 www.sunshineschooltucson.org/

Sunshine School in Oro Valley

Sunshine School 9000 N. Oracle Road Tucson, AZ 85704, Suite 204 (520)742-6874 www.sunshineschoolt...

Northwest Chatter

  • Marana Town Talk: Hot temperatures are here, don’t forget the pool

    Ed Honea, Special to The Explorer

    • icon posted: May 22
  • JTED is a helpful resource for students

    Thelma Grimes, The Explorer

    • icon posted: May 22
  • Such the Spot - The audacious pursuit of dreams

    Darcie Maranich/Special to The Explorer

    • icon Updated: May 19
  • Prime Time Review - 'Kitchen Nightmares' causes chaos for Scottsdale

    Logan Buus/Explorer Intern

    • icon posted: May 19

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Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera read more

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera. A stroller carrying a 14-month-old girl rolled off a slanted train station platform and fell onto the tracks Wednesday, but the girl's mother leaped onto the tracks to rescue her with the help other passengers, transit officials said."What it looks like to us is that the mother became distracted by something, didn't apply the brake on the stroller and the stroller was able to move off the platform and onto the tracks," said Scott Sauer, director of system safety for the Southeastern Pennsylvania Transportation Authority. The accident happened Wednesday afternoon at the 56th Street station of the Market-Frankford Line in west Philadelphia. The platform at the station is slanted slightly for drainage purposes, Sauer said.Surveillance video shows a woman on the eastbound platform with the girl in a jogging stroller, which slowly rolls forward and topples over onto the tracks about 5 feet below. What initially appears to be the girl flying out of the stroller apparently was just a towel or a bag. The stroller comes to rest on the outer rail, which carries no charge. The woman is seen jumping down and lifting the girl to a man waiting on the platform. Other passengers ran to help, and one used an emergency call box to alert SEPTA police, who held an incoming train at the preceding stop.The infant was taken to Children's Hospital of Philadelphia for treatment of a cut on her forehead. Sauer said during a news conference that watching the video was "gut-wrenching.""With the stroller moving at such a slow rate of speed, you know, you want to call out to someone, `Hey, the stroller's moving! Somebody grab the stroller,'" Sauer said. He said the line is one of SEPTA's busiest, with trains running every six to 10 minutes. SEPTA police said no charges will be filed but the accident serves as a reminder for other riders to lock stroller brakes when waiting on platforms.

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera. A...

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