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May 21, 2013
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Displaying results 1 - 25 of 316 for teenagers. Subscribe to this search

  1. article Why--And How--To Boost Your Money IQ

    Thursday, May 9, 2013 4:44 am

    (NAPSI)--Many people might get and keep their hands on more money if they had a better grasp of finances. Consider these statistics from Indiana State University:

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  2. article What's Up UA? - UA Geneticists Find Causes for Severe Childhood Epilepsies

    Wednesday, May 8, 2013 5:09 pm

    Researchers at the University of Arizona have successfully determined the genetic mutations causing severe epilepsies in seven out of 10 children for whom the cause of the disorder could not be determined clinically or by conventional genetic testing.

    Instead of sequencing each gene one at a time, the team used a technique called whole-exome sequencing: Rather than combing through all of the roughly 3 billion base pairs of an individual's entire genome, whole-exome-sequencing deciphers only actual genes, and nearly all of them simultaneously.

    "My initial hope was that we would find something in one out of the 10 children in our study. But a 70 percent success rate is beyond anyone's imagination," said study leader Michael Hammer, who is a research scientist in the UA's Arizona Research Labs Division of Biotechnology and a member of the UA BIO5 Institute.
     
    For Hammer, the research hit very close to home. Just last year, his lab tracked down the mutation that had caused the severe – and ultimately fatal – epilepsy in his teenage daughter. 
     
    "I figured, if we could do this for one child, we could do it for others." Hammer explained. "These are children who have had every test imaginable and tried every possible drug combination, and nobody has figured out where their seizures come from and how to stop them."
     
    The children who participated in the study, published online in the journal Epilepsia, all suffered from severe seizure disorders, and most of them started having seizures within the first year or two after birth.
     
    Unlike individuals afflicted with epilepsy later in life, many of whom can live normal lives with the right medical oversight and medications, early-onset epilepsy can be devastating. Children often develop other severe complications such as intellectual disability, autism and loss of muscle tone or coordination. Early death is not uncommon.
     
    "Because their seizures are not well controlled, and that firestorm of electrical activity in the brain is bad for brain development, the damage can be extensive," added Linda Restifo, a professor in the UAdepartment of neurology and a BIO5 member who co-authored the study. "The earlier the seizures start and the more severe and frequent they are, the more likely they are to leave the child with permanent developmental disability."
     
    "The sooner we can catch problems in children and understand what is causing them, the better the chance we have to try and correct them," Hammer added. 
     
    To identify changes in the DNA that are the most likely cause of the disorders, the team focused on a class of mutations called de novo mutations: "typos" in the DNA sequence that are present only in the child. In order to find such mutations, the study included both parents and their child.
     
    Overall, the team found 15 mutations in nine children, seven of which are known or likely to cause epilepsy. No mutations could be found in one of the children. 
     
    "In four of the patients. we found mutations that were already known to be associated with epilepsy," said Krishna Veeramah, a postdoctoral fellow in Hammer's group and the study's first author. "However, three patients had mutations in genes that were not previously associated with epilepsy in humans but presented plausible explanations for the disorder."
     
    "The fact that we found three genes – in a study involving only 10 subjects – that had never been implicated in epilepsy before suggests that many more genetic defects related to developmental brain disorders remain to be discovered," Veeramah said.  
     
    One of the participants in the study was Ashley Wilhelm, a 14-year-old girl from Phoenix, Ariz., whose seizures started when she was only 5 months old. Her first seizures appeared to be triggered by fever, leading doctors to believe they were just that – a side effect of the fever. 
     
    "But she soon began to have more and more seizures, and they would last half an hour or longer," said her mother, Ann. "We had all sorts of tests done, but the doctors kept saying her brain was normal, and that they didn't see any reason she'd have those seizures."
     
    Ashley, whose development has severely suffered as a consequence of the repeated seizures, was enrolled in the study through her neurologist, Dinesh Talwar, who co-authored the paper.
     
    Even though her treatment is unlikely to change with the new information, the family said the results brought "more relief than we can explain."
     
    "Since insurance wouldn't pay for the testing, and we couldn't afford it on our own, we were very grateful we were able to participate in the study," said Jeff Wilhelm, Ashley's father. "If such a test could be done much earlier, it would ease the pain for everyone involved. What if our son had decided not to consider having children of his own out of concern they might have the disorder?"
     
    "The results from this study have at last given us a breakthrough," said the mother of another participating teenager. "We had pursued every possible avenue to understand what might be responsible for his epilepsy – magnetic resonance imaging, CT scans, searches for gross chromosome abnormalities or markers associated with epilepsy – with no success."
     
    "Although the discovery doesn't yet give us a treatment, it gives us hope for finding one," she said. "As more research is done on this mutation, drugs to control our son's seizures will be identified. If more children with epilepsy can be studied and families with children with similar mutations can organize and share resources, there will be more progress."
     
    Hammer said the approach is applicable to other conditions in which conventional genetic testing has failed to reveal the cause.
     
    "Our work bridges research and clinical practice," he added. "We can sequence all the genes in your genome in a matter of days and report it to the patient's family and the physician. That may make a difference in the treatment and management of the disorder in question."
     
    Centers with the capabilities to do this kind of analysis are few and far between.
     
    "Other centers that do this kind of work will sequence your genome and tell you where and what the mutation is in the DNA sequence, but it's not that simple," Hammer said. "In most cases, we find a mutation in a gene not previously known to cause disease, so we need to perform a follow-up study to find out what that mutation actually does."
     
    To perform these follow-up studies, the UA team has established collaborations with leading scientists at the UA and at other institutions.
     
    "Right now, the benefit to families is primarily to get answers," said Restifo. "The long-term goal is to collect this kind of information from more children, which will hopefully lead to new research into medications that improve brain development and function."
     
    Hammer added: "In the meantime, a molecular diagnosis provides immediate relief to the unnecessary guilt parents might feel for their role in causing their child's suffering. They want answers, not endless doctors visits and tests with negative results, or to have their hopes raised and dashed over and over."
     
    Encouraged by the success of their approach so far, Hammer and his colleagues already have bigger plans. 
     
    "We hope to involve other clinical areas such as cardiology, immunology, gastroenterology – anything that we can apply molecular diagnostics or clinical genomics to at the UA, we want to explore. We want to make the University the core for clinical diagnostics using new sequencing technologies for at least the entire Southwest."
     
    UA pediatric geneticist Robert Erickson, another co-author and member of the UA Steele Children's Research Center added, "these efforts will be very important in the diagnosis of newborns with unusual birth defects."
     

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  3. article Six rules to help keep your teen driver safe

    Monday, May 6, 2013 10:00 pm

    (BPT) - If you worry about the kind of car your teen will drive, you’re not alone.

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  4. article America's Top Charity Influencer

    Thursday, May 2, 2013 4:44 am

    (NAPSI)—It may come as a surprise to some, but the famous face that can encourage people to donate to charity more than any other is that of the First Lady.

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  5. article FDA makes morning after pill more accessible to teenage girls

    Wednesday, May 1, 2013 11:53 am

    The Food and Drug Administration (FDA) is making it easier for teenage girls to get over-the-counter birth control, by allowing Plan B One-Step emergency contraceptive to be sold without a prescription to women 15 years of age and older.

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  6. article Impromptu party planning: How to create great gatherings in 30 minutes or less

    Monday, April 29, 2013 10:00 pm

    (BPT) - Parents have never been more crunched for time. Balancing work demands with parental duties is complex – 56 percent of working moms and 50 percent of working dads say they find it very or somewhat difficult to balance these responsibilities, according to a 2013 report about modern parenthood from the Pew Research Center. But just because you’re time strapped doesn’t mean you need to stress when it comes time to host after-school activities or weekend gatherings with friends and family. With a few key strategies, even impromptu parties are a snap to pull together.

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  7. article Police Beat -- Week of April 15

    Wednesday, April 17, 2013 4:00 am

    Oro Valley

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  8. article Disappointed in LaWall

    Wednesday, April 10, 2013 4:00 am

    I was disappointed in Pima County District Attorney Barbara LaWall’s lack of interest in righting a more than 40-year wrong recently.

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  9. article Gov. Brewer signs legislation to combat production, use of dangerous drugs

    Thursday, April 4, 2013 9:43 am

    Gov. Jan Brewer signed into law House Bill 2327, legislation that gives law enforcement officers another critical tool to attack the production and use of so-called “Spice,” “K2” and other synthetic drugs in our communities.

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  10. article ‘Croods’ a step backwards for DreamWorks

    Wednesday, April 3, 2013 4:00 am

    DreamWorks Animation has always strived to tell stories that can appeal to all ages. Their latest animated comedy, “The Croods,” will surely be enjoyed by anybody who is younger than 10. Unlike “Shrek” and “Kung-Fu Panda” though, it lacks the wit and innovation for older audiences. Compared to most Saturday morning cartoons, the film won’t passionately annoy parents that get dragged to the theater. But in an era where more and more adults are attending animated features without accompanying children, “The Croods” feels like a step backwards for DreamWorks.

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  11. article County attorney announces April as Month of Awareness and Action to aid victims crime

    Thursday, March 28, 2013 10:35 am

    Pima County Attorney Barbara LaWall encourages the community to participate this April in the many different outreach and educational activities that support victims of crime and promote efforts to prevent violence.

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  12. article Five Marana officers receive lifesaving award

    Wednesday, March 27, 2013 4:00 am

    In a new program introduced by Marana Police Chief Terry Rozema, officers are being recognized for acts of valor and dedication in the line of duty. The first of the award recipients have already been selected. 

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  13. article The Talk Just Got a Little Easier

    Friday, March 22, 2013 10:04 am

    (NewsUSA) - When you hand car keys to your teenager for the first time, your heart races as you think of what could happen. The fact is that car accidents are the number-one cause of death among teens in the U.S., so it's important to communicate the gravity of this newfound responsibility.

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  14. article Tough lessons in tough times

    Wednesday, March 20, 2013 4:00 am

    On Sunday, an unusual day for a court to be held in Ohio, a judge found two high school football players guilty of rape. In what became a short trial that divided the football-crazed Rust Belt town of Steubenville, Trent Mays, 17, and Ma’lik Richmond, 16, were found guilty of raping a drunk 16-year-old girl.

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  15. article Legally Blind Racer Forges Ahead as Musher -- and Reader

    Thursday, March 14, 2013 12:54 pm

    (NewsUSA) - Rachael Scdoris is a competitive dogsled racer and -- thanks to the National Library Service for the Blind and Physically Handicapped (NLS), the Library of Congress -- an avid reader.

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  16. article When ordinary distraction is something more: diagnosing ADHD

    Monday, March 11, 2013 10:00 pm

    (BPT) - What parent hasn’t had to call a child’s name more than once to get his attention? Or wondered how she can still be “bouncing off the walls” at the end of a long, tiring day. Moments of intense activity or occasional inattention are typical kid behavior, but for some children the problem is extreme and impairing. How can parents tell if their child’s energy or distraction is ordinary or something more?

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  17. article A hysterectomy by robot success

    Wednesday, March 6, 2013 4:00 am

    Megan Traquair’s life runs non-stop.  She works full-time, and she and her husband are raising two teenagers.  Her favorite relaxations are to garden, read and work out.  Spare time?  What’s that?

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  18. article Be Sure to Discuss All Your Symptoms With Your Doctor - The Highs and Lows of Bipolar Disorder

    Tuesday, March 5, 2013 11:00 pm

    (BPT) - Bipolar disorder is a condition of extremes that can affect both how you feel and how you act. It includes bipolar mania–extremely high moods that last at least a week–and bipolar depression–depressive moods or lows that last for at least two weeks and for most of the day, nearly every day. Most people suffering from bipolar disorder experience more lows than highs, which can make manic symptoms even more difficult to spot.

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  19. article Innovations inspire high school girls to become next generation of female innovators, change the world through STEM

    Monday, March 4, 2013 11:00 pm

    (BPT) - When the high school class of 2014 graduates from college in five years, more than 8 million jobs will be available in the fields of science, technology, engineering and math (STEM). For students today, STEM is their future.

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  20. article Signs Your Teen is in Trouble and What to Do About It

    Sunday, March 3, 2013 11:00 pm

    (StatePoint) Being a teenager is never easy, but for some kids, it is excruciating. For parents, being able to tell the difference between normal growing pains and real trouble is crucial.

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  21. article Pima County Sheriff's Department to hold Dispose-A-Med

    Friday, March 1, 2013 12:37 pm

    In 2012, the Pima County Sheriff’s Department collected a total of 1,553 pounds of unused or expired prescription drugs. Why is proper disposal of these substances so important? There are several factors that should be taken into account.

  22. article How To Keep Siblings Sweet

    Thursday, February 14, 2013 4:44 am

    (NAPSI)—Getting brothers and sisters to look out for each other can be easier than many parents realize. It helps to plan family activities that are fun for everyone. If your kids have good experiences together, it can be a buffer when they come into conflict. It’s easier to work things out with someone with whom you share warm memories.

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  23. How To Keep Siblings Sweet

    Victoria Justice stars as a teenager forced to look after her little brother in the family comedy Fun Size. (NAPS)

  24. article What To Look For In A Legal Benefits Plan

    Thursday, February 7, 2013 4:44 am

    (NAPSI)—It may come as a surprise to some, but 57 million full-time working Americans experienced at least one significant legal event in the past 12 months, and nearly half faced their legal issues and challenges without professional help, according to a national study.

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  25. article ‘Warm Bodies’ an epic, believable love story

    Wednesday, February 6, 2013 4:00 am

    Zombies are terrible characters. That’s not to say there haven’t been plenty of good movies featuring zombies like “28 Days Later,” “Shaun of the Dead,” “Zombieland,” and the George A. Romero classics.

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Sunshine School in Oro Valley read more

Sunshine School 9000 N. Oracle Road Tucson, AZ 85704, Suite 204 (520)742-6874 www.sunshineschooltucson.org/

Sunshine School in Oro Valley

Sunshine School 9000 N. Oracle Road Tucson, AZ 85704, Suite 204 (520)742-6874 www.sunshineschoolt...

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  • Such the Spot - The audacious pursuit of dreams

    Darcie Maranich/Special to The Explorer

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  • Prime Time Review - 'Kitchen Nightmares' causes chaos for Scottsdale

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  • Oro Valley Town Talk: The Oro Valley Aquatic Center: Another success story

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Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera read more

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera. A stroller carrying a 14-month-old girl rolled off a slanted train station platform and fell onto the tracks Wednesday, but the girl's mother leaped onto the tracks to rescue her with the help other passengers, transit officials said."What it looks like to us is that the mother became distracted by something, didn't apply the brake on the stroller and the stroller was able to move off the platform and onto the tracks," said Scott Sauer, director of system safety for the Southeastern Pennsylvania Transportation Authority. The accident happened Wednesday afternoon at the 56th Street station of the Market-Frankford Line in west Philadelphia. The platform at the station is slanted slightly for drainage purposes, Sauer said.Surveillance video shows a woman on the eastbound platform with the girl in a jogging stroller, which slowly rolls forward and topples over onto the tracks about 5 feet below. What initially appears to be the girl flying out of the stroller apparently was just a towel or a bag. The stroller comes to rest on the outer rail, which carries no charge. The woman is seen jumping down and lifting the girl to a man waiting on the platform. Other passengers ran to help, and one used an emergency call box to alert SEPTA police, who held an incoming train at the preceding stop.The infant was taken to Children's Hospital of Philadelphia for treatment of a cut on her forehead. Sauer said during a news conference that watching the video was "gut-wrenching.""With the stroller moving at such a slow rate of speed, you know, you want to call out to someone, `Hey, the stroller's moving! Somebody grab the stroller,'" Sauer said. He said the line is one of SEPTA's busiest, with trains running every six to 10 minutes. SEPTA police said no charges will be filed but the accident serves as a reminder for other riders to lock stroller brakes when waiting on platforms.

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera

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