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May 23, 2013
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      At age 29, Joel Sanchez is fighting the fight of his life as he struggles with ALS.

      • posted: May 23
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  1. article Abrams has made the best ‘Star Trek’ movie

    Wednesday, May 22, 2013 4:00 am

    On paper, J.J. Abrams’ 2009 “Star Trek” is one of those movies that should have crashed and burned. A reboot of a beloved franchise with younger, lesser-known actors stepping into the shoes of an iconic cast of characters. The fact that Abrams went on record stating that he was never a huge “Star Trek” fan didn’t bode well either. Against all odds, though, Abrams not only produced a great “Star Trek” picture, but quite possibly the best “Star Trek” ever made. That’s right, even better than “Star Trek II: The Wrath of Khan.” 

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  2. article What to look for in your next smartphone

    Tuesday, May 21, 2013 5:00 pm

    (BPT) - Seventy-nine percent of smartphone users have their phones on or near them all but two hours of the day when they’re awake, according to a recent IDC Research report. For many, smartphone use is now a way of life, making it even more important to think carefully before you choose your next one. Today’s market is competitive, and new phones, such as the BlackBerry Z10 and BlackBerry Q10, are emerging.

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  3. article Ask the Pharmacist: Controlling asthma during allergy season

    Monday, May 20, 2013 5:00 pm

    (BPT) - The sun is shining, flowers are blooming, and pollen counts are soaring ... and that means millions of Americans are dealing with the sneezing and wheezing that comes with seasonal allergies. While allergies are sometimes considered an uncomfortable nuisance, for the 25 million Americans with asthma, seasonal allergies can trigger serious attacks that if not managed properly could lead to a visit to the ER. In fact, asthma is responsible for half a million hospitalizations each year – 60 percent of which are caused by patients not taking their medication as prescribed.

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  4. article Following Warren Buffet's Lead in Energy Deregulation

    Monday, May 20, 2013 6:17 am

    (NewsUSA) - According to recent reports, Warren Buffet has identified energy deregulation as the next big financial opportunity to reverberate around the country. Similarly, former GE Chairman Jack Welch described deregulation as "the next biggest thing since the Internet."

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  5. article (May 19) Today's Top Headlines - Despite controversial week, Obama's poll number remain unchanged

    Sunday, May 19, 2013 8:54 am

    According to a CNN report, President Barack Obama comes out of what is likely the worst week of his presidency with his approval rating holding steady, according to a new national poll.

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  6. article Encourage Kids to Have Gadget-Free Fun this Summer

    Saturday, May 18, 2013 10:00 pm

    (StatePoint) You may remember your parents telling you to turn off the television and go outside or read a book. But these days, it’s harder than ever to separate kids from media devices, especially as their options become more mobile.

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  7. article (May 17) Today's Top Headlines - Lawmakers want answers on IRS decisions

    Friday, May 17, 2013 9:27 am

    According to a CBS report this morning, Irate lawmakers accused the acting IRS commissioner of misleading them about the agency's selective scrutiny of tea party-affiliated groups, demanding to know who was responsible and why no one told Congress.

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  8. article Restaurants Find Success with Daily Deals

    Thursday, May 16, 2013 10:00 pm

    (StatePoint) With so many options competing for the attention of diners, local restaurants are increasingly having success offering daily deals.

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  9. youtube Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera

    Thursday, May 16, 2013 10:02 am

    Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera. A stroller carrying a 14-month-old girl rolled off a slanted train station platform and fell onto the tracks Wednesday, but the girl's mother leaped onto the tracks to rescue her with the help other passengers, transit officials said."What it looks like to us is that the mother became distracted by something, didn't apply the brake on the stroller and the stroller was able to move off the platform and onto the tracks," said Scott Sauer, director of system safety for the Southeastern Pennsylvania Transportation Authority. The accident happened Wednesday afternoon at the 56th Street station of the Market-Frankford Line in west Philadelphia. The platform at the station is slanted slightly for drainage purposes, Sauer said.Surveillance video shows a woman on the eastbound platform with the girl in a jogging stroller, which slowly rolls forward and topples over onto the tracks about 5 feet below. What initially appears to be the girl flying out of the stroller apparently was just a towel or a bag. The stroller comes to rest on the outer rail, which carries no charge. The woman is seen jumping down and lifting the girl to a man waiting on the platform. Other passengers ran to help, and one used an emergency call box to alert SEPTA police, who held an incoming train at the preceding stop.The infant was taken to Children's Hospital of Philadelphia for treatment of a cut on her forehead. Sauer said during a news conference that watching the video was "gut-wrenching.""With the stroller moving at such a slow rate of speed, you know, you want to call out to someone, `Hey, the stroller's moving! Somebody grab the stroller,'" Sauer said. He said the line is one of SEPTA's busiest, with trains running every six to 10 minutes. SEPTA police said no charges will be filed but the accident serves as a reminder for other riders to lock stroller brakes when waiting on platforms.
  10. article (May 16) Today's Top Headlines - Baby falls on SEPTA train tracks

    Thursday, May 16, 2013 10:00 am

    A 14-month-old girl was hospitalized after falling onto commuter train tracks in West Philadelphia.

    1 image 1 youtube

  11. article Home chefs use new technology to cook with ease

    Wednesday, May 15, 2013 5:00 pm

    (BPT) - Home cooks are spending more time in their own kitchens and less time dining out, according to the January Monthly Measuring Cup Trend Report. Nearly half of surveyed consumers said they’re dining out less this year than they did in 2012 and are relying more on their cooking skills at home. Fortunately, technology makes it easier than ever for home chefs to prep and cook meals at home and clean up conveniently and efficiently afterward.

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  12. article When Hot Flashes Meet Summer Heat: Tips To Help Keep You Cool

    Wednesday, May 15, 2013 4:44 am

    (NAPSI)If youre among the nearly 75 percent of menopausal women who suffer from hot flashes,1 it can be tough to enjoy the sunny weather worrying about a sudden hot flash in summertime. And since hot weather tends to be a common hot flash trigger,2 these sudden feelings of warmth can be exacerbated. But, with just a little planning and preparation you can get on the right track to an enjoyable summer.

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  13. article Macdonald wins big in track championships

    Wednesday, May 15, 2013 4:00 am

    For many athletes, winning state involves countless hours of hard practice, dedication and training. For Sarah Macdonald, practice is only part of the reason for her cross country and track successes.

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  14. article Save money and do a world of good with reusable containers

    Tuesday, May 14, 2013 10:00 pm

    (BPT) - Even as the country moves out of the great recession, many Americans are still in a money-saving mode – looking to conserve wherever possible.

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  15. article Wall-mounted sliding door 'reflects' a genius design solution

    Monday, May 13, 2013 10:00 pm

    (BPT) - Like many couples who share a bathroom, one Arizona couple was frustrated by the space that was compromised by a swinging bathroom door. The open door swung into the bathroom vanity and took up too much space in a very traditional bathroom.

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  16. article Creative Ways to Keep Kids Learning this Summer

    Sunday, May 12, 2013 10:00 pm

    (StatePoint) For families, summertime is all about active fun -- from vacations to ballgames, and fireworks to poolside picnics. But being on-the-go can mean lots of downtime in transit and waiting for activities to start.

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  17. article Make Your Next Family Vacation Truly Meaningful

    Saturday, May 11, 2013 7:49 pm

    If you’re tired of taking the same old kinds of vacations, consider looking into more meaningful travel alternatives. Whatever your interests are, there are great ways to infuse your vacation with purpose.

  18. article PCC Track Earns Five Region Titles on Final Day

    Friday, May 10, 2013 8:37 am

    The Pima Community College track & field teams each took second place and produced five more region champions on Thursday in the final day of the Region I Championships at Mesa Community College. The Aztecs had nine total region champions to close out competition.

  19. article Army Amputee Continues To Serve Through Adaptive Sports And Reconditioning

    Thursday, May 9, 2013 4:44 am

    (NAPSI)—Seven months after joining the Army, Sgt. Ryan McIntosh stepped on an improvised explosive device during a routine orchard-clearing mission in Afghanistan. He came home with a deeper commitment to the uniform, despite losing his right leg below the knee.

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  20. article What's Up UA? - UA Geneticists Find Causes for Severe Childhood Epilepsies

    Wednesday, May 8, 2013 5:09 pm

    Researchers at the University of Arizona have successfully determined the genetic mutations causing severe epilepsies in seven out of 10 children for whom the cause of the disorder could not be determined clinically or by conventional genetic testing.

    Instead of sequencing each gene one at a time, the team used a technique called whole-exome sequencing: Rather than combing through all of the roughly 3 billion base pairs of an individual's entire genome, whole-exome-sequencing deciphers only actual genes, and nearly all of them simultaneously.

    "My initial hope was that we would find something in one out of the 10 children in our study. But a 70 percent success rate is beyond anyone's imagination," said study leader Michael Hammer, who is a research scientist in the UA's Arizona Research Labs Division of Biotechnology and a member of the UA BIO5 Institute.
     
    For Hammer, the research hit very close to home. Just last year, his lab tracked down the mutation that had caused the severe – and ultimately fatal – epilepsy in his teenage daughter. 
     
    "I figured, if we could do this for one child, we could do it for others." Hammer explained. "These are children who have had every test imaginable and tried every possible drug combination, and nobody has figured out where their seizures come from and how to stop them."
     
    The children who participated in the study, published online in the journal Epilepsia, all suffered from severe seizure disorders, and most of them started having seizures within the first year or two after birth.
     
    Unlike individuals afflicted with epilepsy later in life, many of whom can live normal lives with the right medical oversight and medications, early-onset epilepsy can be devastating. Children often develop other severe complications such as intellectual disability, autism and loss of muscle tone or coordination. Early death is not uncommon.
     
    "Because their seizures are not well controlled, and that firestorm of electrical activity in the brain is bad for brain development, the damage can be extensive," added Linda Restifo, a professor in the UAdepartment of neurology and a BIO5 member who co-authored the study. "The earlier the seizures start and the more severe and frequent they are, the more likely they are to leave the child with permanent developmental disability."
     
    "The sooner we can catch problems in children and understand what is causing them, the better the chance we have to try and correct them," Hammer added. 
     
    To identify changes in the DNA that are the most likely cause of the disorders, the team focused on a class of mutations called de novo mutations: "typos" in the DNA sequence that are present only in the child. In order to find such mutations, the study included both parents and their child.
     
    Overall, the team found 15 mutations in nine children, seven of which are known or likely to cause epilepsy. No mutations could be found in one of the children. 
     
    "In four of the patients. we found mutations that were already known to be associated with epilepsy," said Krishna Veeramah, a postdoctoral fellow in Hammer's group and the study's first author. "However, three patients had mutations in genes that were not previously associated with epilepsy in humans but presented plausible explanations for the disorder."
     
    "The fact that we found three genes – in a study involving only 10 subjects – that had never been implicated in epilepsy before suggests that many more genetic defects related to developmental brain disorders remain to be discovered," Veeramah said.  
     
    One of the participants in the study was Ashley Wilhelm, a 14-year-old girl from Phoenix, Ariz., whose seizures started when she was only 5 months old. Her first seizures appeared to be triggered by fever, leading doctors to believe they were just that – a side effect of the fever. 
     
    "But she soon began to have more and more seizures, and they would last half an hour or longer," said her mother, Ann. "We had all sorts of tests done, but the doctors kept saying her brain was normal, and that they didn't see any reason she'd have those seizures."
     
    Ashley, whose development has severely suffered as a consequence of the repeated seizures, was enrolled in the study through her neurologist, Dinesh Talwar, who co-authored the paper.
     
    Even though her treatment is unlikely to change with the new information, the family said the results brought "more relief than we can explain."
     
    "Since insurance wouldn't pay for the testing, and we couldn't afford it on our own, we were very grateful we were able to participate in the study," said Jeff Wilhelm, Ashley's father. "If such a test could be done much earlier, it would ease the pain for everyone involved. What if our son had decided not to consider having children of his own out of concern they might have the disorder?"
     
    "The results from this study have at last given us a breakthrough," said the mother of another participating teenager. "We had pursued every possible avenue to understand what might be responsible for his epilepsy – magnetic resonance imaging, CT scans, searches for gross chromosome abnormalities or markers associated with epilepsy – with no success."
     
    "Although the discovery doesn't yet give us a treatment, it gives us hope for finding one," she said. "As more research is done on this mutation, drugs to control our son's seizures will be identified. If more children with epilepsy can be studied and families with children with similar mutations can organize and share resources, there will be more progress."
     
    Hammer said the approach is applicable to other conditions in which conventional genetic testing has failed to reveal the cause.
     
    "Our work bridges research and clinical practice," he added. "We can sequence all the genes in your genome in a matter of days and report it to the patient's family and the physician. That may make a difference in the treatment and management of the disorder in question."
     
    Centers with the capabilities to do this kind of analysis are few and far between.
     
    "Other centers that do this kind of work will sequence your genome and tell you where and what the mutation is in the DNA sequence, but it's not that simple," Hammer said. "In most cases, we find a mutation in a gene not previously known to cause disease, so we need to perform a follow-up study to find out what that mutation actually does."
     
    To perform these follow-up studies, the UA team has established collaborations with leading scientists at the UA and at other institutions.
     
    "Right now, the benefit to families is primarily to get answers," said Restifo. "The long-term goal is to collect this kind of information from more children, which will hopefully lead to new research into medications that improve brain development and function."
     
    Hammer added: "In the meantime, a molecular diagnosis provides immediate relief to the unnecessary guilt parents might feel for their role in causing their child's suffering. They want answers, not endless doctors visits and tests with negative results, or to have their hopes raised and dashed over and over."
     
    Encouraged by the success of their approach so far, Hammer and his colleagues already have bigger plans. 
     
    "We hope to involve other clinical areas such as cardiology, immunology, gastroenterology – anything that we can apply molecular diagnostics or clinical genomics to at the UA, we want to explore. We want to make the University the core for clinical diagnostics using new sequencing technologies for at least the entire Southwest."
     
    UA pediatric geneticist Robert Erickson, another co-author and member of the UA Steele Children's Research Center added, "these efforts will be very important in the diagnosis of newborns with unusual birth defects."
     

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  21. article McCain’s visit to Oro Valley

    Wednesday, May 8, 2013 4:00 am

    Senator McCain visited Oro Valley this past week. During his initial remarks on a host of topics, he twice mentioned foreign visitors over-extending their visas, and we are not able to track them. 

  22. article US housing market passes half way mark in return of ‘normal’

    Wednesday, May 8, 2013 12:00 am

    Most of us already realize “normal” is relative. Yet, we are only human. And as such, we can scarcely stop ourselves from the very-human behavior of seizing every available opportunity to try to quantify and define the term.

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  23. article The ‘write’ way to cope with keeping a journal

    Wednesday, May 8, 2013 12:00 am

    Nineteenth century author Henry David Thoreau kept a journal of his reflections for the last 25 years of his life.

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  24. article Make warm-weather chores a breeze with these tips

    Tuesday, May 7, 2013 10:00 pm

    (BPT) - Warm weather brings everyone outdoors - grilling on the deck, playing on the lawn and savoring beautiful gardens. To create these beautiful outdoor spaces, the experts at Lowe’s offer four easy, affordable projects you can do yourself. Follow these tips to make sure your outdoor spaces are in tip-top shape by summer’s end.

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  25. article Simple ways to reduce excess sugar in your diet this summer

    Tuesday, May 7, 2013 10:00 pm

    (BPT) - Warm weather offers many sweet delights, from trips to the beach and more free time, to seasonal foods and soirees with family and friends. Unfortunately, many of the foods we commonly associate with spring and summer are high in added sugars. Hidden sugar in summer foods can make it a challenge to regulate calories and stay on track with your health goals.

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Sunshine School in Oro Valley read more

Sunshine School 9000 N. Oracle Road Tucson, AZ 85704, Suite 204 (520)742-6874 www.sunshineschooltucson.org/

Sunshine School in Oro Valley

Sunshine School 9000 N. Oracle Road Tucson, AZ 85704, Suite 204 (520)742-6874 www.sunshineschoolt...

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  • Marana Town Talk: Hot temperatures are here, don’t forget the pool

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    • icon posted: May 22
  • JTED is a helpful resource for students

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    • icon posted: May 22
  • Such the Spot - The audacious pursuit of dreams

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Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera read more

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera. A stroller carrying a 14-month-old girl rolled off a slanted train station platform and fell onto the tracks Wednesday, but the girl's mother leaped onto the tracks to rescue her with the help other passengers, transit officials said."What it looks like to us is that the mother became distracted by something, didn't apply the brake on the stroller and the stroller was able to move off the platform and onto the tracks," said Scott Sauer, director of system safety for the Southeastern Pennsylvania Transportation Authority. The accident happened Wednesday afternoon at the 56th Street station of the Market-Frankford Line in west Philadelphia. The platform at the station is slanted slightly for drainage purposes, Sauer said.Surveillance video shows a woman on the eastbound platform with the girl in a jogging stroller, which slowly rolls forward and topples over onto the tracks about 5 feet below. What initially appears to be the girl flying out of the stroller apparently was just a towel or a bag. The stroller comes to rest on the outer rail, which carries no charge. The woman is seen jumping down and lifting the girl to a man waiting on the platform. Other passengers ran to help, and one used an emergency call box to alert SEPTA police, who held an incoming train at the preceding stop.The infant was taken to Children's Hospital of Philadelphia for treatment of a cut on her forehead. Sauer said during a news conference that watching the video was "gut-wrenching.""With the stroller moving at such a slow rate of speed, you know, you want to call out to someone, `Hey, the stroller's moving! Somebody grab the stroller,'" Sauer said. He said the line is one of SEPTA's busiest, with trains running every six to 10 minutes. SEPTA police said no charges will be filed but the accident serves as a reminder for other riders to lock stroller brakes when waiting on platforms.

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera

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