Close
Welcome!
Login|Signup
Login|My Dashboard|Register
Logout|My Dashboard
May 22, 2013
Contact | About | Subscribe | Advertise | Work for The Explorer | E-Edition | Newsletter Signup
Clear
90°
Clear
Googleplus Facebook Twitter Mobile Version Facebook
  • HOME
    • CONTACT
    • ADVERTISE WITH US
    • ABOUT THE EXPLORER
    • SUBSCRIBE
  • NEWS
    • TODAY'S HEADLINES
    • ORO VALLEY
    • MARANA
    • ANNOUNCEMENTS
    • SUBMIT NEWS

    Top Story

    • Councilman Zinkin defends trip

      Oro Valley Councilman Mike Zinkin is looking to clear his name after comments made earlier this month by Mayor Satish Hiremath regarding the c…

      • posted: May 22
      • Comments (1)
    rss

    More headlines

    • Young student heroes

    • Three top tips for summer travel

    • Oro Valley budget passes: Police funding a hot item

    • New Northwest Fire Chief Brandt discusses department’s direction

  • BUSINESS
    • LOCAL BUSINESS NEWS
    • STOCK MARKET
    • SUBMIT RELEASE

    Top Story

    • The Parish has relaxed atmosphere with southern food and drinks

      One of only a couple gastropubs on the Northwest side of Tucson, The Parish, has made its mark by serving a variety of southern dishes, beers …

      • Updated: May 15
      • Comments (0)
    rss

    More headlines

    • Tanner Custom Leather makes hand-tooled western products

    • The Joint works to offer affordable chiropractic care

    • Hilton Tucson El Conquistador announces its summer program

    • May is Small Business Month: Do You Have What it Takes to Start Your Own Business?

  • SPORTS
    • PREP SPORTS
    • UA WILDCATS
    • TUCSON PADRES

    Top Story

    • Padres beat Omaha 7-5

      Tucson Padres Game Summary May 22, 2013

      • Updated: 10:32 pm
      • Comments (0)
    rss

    More headlines

    • UA Basketball - Stoudamire prefers college over coaching pros

    • Padres fall to Iowa 7-3

    • Padres drop Iowa 9-8 on Friday

    • Padres lose to Iowa 1-0

  • FEATURES
    • NORTHWEST CHATTER
    • AGING WELL
    • REAL ESTATE
    • POLICE & CRIME

    Top Story

    • Sea Life Aquarium in Phoenix has state’s largest collection of jellyfish

      Sea Life Aquarium at Arizona Mills is giving kids and adults a sneak peek into the life of a sea creature with no brain and no heart — jellyfish.

      • Updated: 10:05 am
      • Comments (0)
    rss

    More headlines

    • Turn on the tap! Drink more water for better health

    • Owners of energy-efficient homes are less likely to default on mortgages

    • Three top tips for summer travel

    • Featured Community: Rancho Vistoso

  • THINGS TO DO
    • CALENDAR OF EVENTS
    • MOVIE REVIEWS
    • RESTAURANT REVIEWS
    • SUBMIT A REVIEW

    Top Story

    • Abrams has made the best ‘Star Trek’ movie

      On paper, J.J. Abrams’ 2009 “Star Trek” is one of those movies that should have crashed and burned. A reboot of a beloved franchise with young…

      • Updated: 11:35 am
      • Comments (0)
    rss

    More headlines

    • Sippin' Social: The Explorer visits Metropolitan Grill

    • “The List: A Musical”

    • The Guide -- Week of May 22

    • Saturday Puzzles 5-18-13

  • OPINION
    • COLUMNS
    • LETTERS TO EDITOR
    • SUBMIT A LETTER

    Top Story

    • JTED is a helpful resource for students

      Over the next week, thousands of young adults will walk across a stage to receive their high school diplomas. Many of them will take that spec…

      • posted: May 22
      • Comments (0)
    rss

    More headlines

    • Marana Town Talk: Hot temperatures are here, don’t forget the pool

    • Respect your servers

    • Guest Column: Be realistic in crediting schools like BASIS

    • Oro Valley Town Talk: The Oro Valley Aquatic Center: Another success story

  • MARKETPLACE
    • CLASSIFIEDS
    • SHOP CATALINA
    • SHOP ORO VALLEY
    • SHOP MARANA

    Most Recent

    • Camp Bow Wow

      Tucson Airport Shuttle Service is available – if you board your dog with us while you are away. We will pick you, your luggage and dog(s) up, …

      • posted: May 22
      • Comments (0)
    • Third cash mob planned

    • Koko FitClub offers summer camp for teens

    • Kyger Orthodontics: Invisalign Teen

    • Catalina Community Services: Improving lives. Inspiring futures.

  • BLOGS
    • THE DOCTOR IS IN
    • GADGET MAGNET
    • WHAT'S UP UA
    • MUSIC LANDSCAPE
    • PET NEWS
    • PRIME TIME REVIEW
    • SUCH THE SPOT

    Most Recent

    • Pet News - Honor sacrifice, service at Memorial Day Dog Walk

      Pima Animal Care Center thanks the veterans who have made it possible for the rest of us to have the freedom to support community causes that …

      • posted: May 21
      • Comments (0)
    • Gadget Magnet - Data Doctors talk about how to maximize your mobile battery life

    • Such the Spot - The audacious pursuit of dreams

    • Prime Time Review - 'Kitchen Nightmares' causes chaos for Scottsdale

    • Pet News - Adore-a-Bull Adoption Party

  • VIDEO
    • BUSINESS SPOTLIGHT

    Most Recent

    • Country Thunder, Day 3: Brice and Keith steal the show

      Toby Keith and Lee Brice will be a tough act to follow today, the final day of Country Thunder in Florence.

      • Updated: May 02
      • Comments (0)
    rss

    More headlines

    • Country Thunder: Day 2 wrap-up: Eric Church shines

    • Country Thunder starts out with a bang

    • Cadets attend academy

    • Pilates instructor helps her clients improve strength

  • SPECIAL SECTIONS
    • GO! EXPLORE
    • KIDS CAMP
    • CATALINA STATE PARK
    • HEALTH & WELLNESS
    • BEST OF THE NW
    • ACTIVE LIVING
    • HOME & GARDEN
    • AUTOMOTIVE
    • WOMEN IN BUSINESS
    • DISCOVER THE NW

    Most Recent

    • Sea Life Aquarium in Phoenix has state’s largest collection of jellyfish

      Sea Life Aquarium at Arizona Mills is giving kids and adults a sneak peek into the life of a sea creature with no brain and no heart — jellyfish.

      • Updated: 10:05 am
      • Comments (0)
    rss

    More headlines

    • Three top tips for summer travel

    • Disneyland is just a short ride away from Tucson

    • Westin La Paloma makes summer plans

    • Summer heat wears down the automobile

  • JOBS
  • Home
Search
Advanced Search Options
Date Options
Sort Options
Extended Filters








Displaying results 1 - 25 of 271 for trial. Subscribe to this search

  1. article (May 21) Today's Top Headlines - Arias pleads for life, promises to do good in prison

    Tuesday, May 21, 2013 11:28 am

    In a plea for her life on Tuesday, convicted murderer Jodi Arias said if she is sentenced to life instead of death, she will make a positive impact on the prison system.

    1 image

  2. article (May 20) Today's Top Headlines - Defense asks for mistrial, Arias to testify Tuesday

    Monday, May 20, 2013 9:23 am

    The trial that has gained international attention, grabbing the top headlines daily and showing a mixture of sex, deceit and murder, is now entering the final phase.

    1 image

  3. article This Year's Summer Blockbusters Aim to be Bigger than Ever

    Sunday, May 19, 2013 10:00 pm

    (StatePoint) This year’s summer blockbuster season is shaping up to be a big one, full of some of the year’s most highly anticipated films.

    1 image

  4. article (May 16) Jodi Arias likely to be sentenced to death

    Thursday, May 16, 2013 10:05 am

    It didn't take long for a jury on Wednesday to conclude that how Mesa resident Travis Alexander died in 2008, was indeed cruel.

    1 image

  5. article (May 15) Jodi Arias trial set to resume in Phoenix

    Wednesday, May 15, 2013 12:28 pm

    The penalty phase of the Jodi Arias trail is set to resume Wednesday.

    1 image

  6. article Respect your servers

    Wednesday, May 15, 2013 4:00 am

    Several months back, I wrote an editorial on bad customer service, and the trials and tribulations we go through with automated services, a lack of caring from certain businesses, and the trouble we sometimes go through to get quality service.

    1 image

  7. article (May 10) Today's Top Headlines - Arias trial to resume next week

    Friday, May 10, 2013 11:23 am

    After a closed-door meeting with the judge on Thursday, the second phase of the Jodi Arias trial was abruptly canceled.

    1 image

  8. article Prime Time Review - The future of the online movie market

    Friday, May 10, 2013 8:53 am

    The online streaming industry is growing and growing every year. Standing at the forefront of this online explosion is Netflix, the well known provider of both online streaming of thousands of different programs ranging from movies, to T.V. shows, and documentaries as well as in home, through the mail deliveries of their content. Netflix began the road to online kingship back in 1997, when the company began as a traditional through the mail provider. By 1999 the company had introduced a monthly subscription policy and now operates on both monthly payment and unlimited online streaming. Over the past decade or so, Netflix has found its way into the homes of many families, college students, and anyone else who enjoys video entertainment. Netflix has been able to stand amongst the forefront of much of the development of the in-home and delivery movie craze, but this rise to the top has not been one without trials and setbacks.

    1 image

  9. article (May 8) Today's top headlines - Jodi Arias found guilty, new phase in trial begins

    Wednesday, May 8, 2013 2:56 pm

    It took just over 15 hours for a 12-member jury to find accused boyfriend killer, Jodi Arias, guilty of first-degree murder.

    1 image

  10. article How to support your friend in a split

    Wednesday, May 1, 2013 10:00 pm

    (BPT) - When a marriage ends in divorce, it’s not just the couple who is involved. Friends and family members are also part of the process and often play many different parts – from objective confidant to reliable “vent-ee.” If you’re suddenly or unexpectedly thrown into this role, what help are you prepared to offer? Support can make a critical difference to your friend, but unfortunately, doesn’t come with how-to manual.

    1 image

  11. article Advancements In Metastatic Melanoma

    Thursday, April 25, 2013 4:44 am

    (NAPSI)Cancer is one of the most widespread diseases and the leading cause of death worldwide. Nearly one in 24 Americans are living with some form of cancer, so chances are you know someone with the disease.

    1 image

  12. article What's Up UA? - UA Spin-Off to Test Cancer-Preventing Drug Combination

    Tuesday, April 23, 2013 9:38 am

    Cancer Prevention Pharmaceuticals, Inc., or CPP, has helped launch a phase-III clinical trial to test the efficacy of a combination drug that has shown promise of preventing colon cancer. CPP was founded in 2008 to apply decades' worth of systematic, basic research led by University of Arizona professor emeritus Eugene Gerner and former UA researcher Frank Meyskens to improve clinical practice. 

    During the trial, which is funded by the National Cancer Institute, 1,340 colon cancer survivors will receive daily treatment for three years to prevent the occurrence of colorectal cancer or high-risk polyps and compare the effects to a placebo group. 
     
    "Our long-term vision is to change the status quo from treating and managing cancer to intervening before cancer manifests and prevent it altogether," said Jeffrey Jacob, founding CEO of Cancer Prevention Pharmaceuticals. "The idea is just like in the approach to heart disease: Instead of waiting for heart attack or stroke to happen, we give patients cholesterol-lowering or blood pressure-lowering medicine to prevent those events from happening in the first place."
     
    In addition to colorectal cancer, the same treatment approach has shown promise in preventing prostate, skin and possibly other cancers as well. Colorectal cancer affects about 1 million people in the U.S., Jacob said. 
     
    "Our two-drug-combination targets different pathways that are important in cancer development," explained CPP co-founder Eugene Gerner, who retired from the department of cellular and molecular medicine in the UA College of Medicine last year. "Over years of research using cell cultures and mouse models in the lab, we have been able to systematically elucidate the molecular pathways underlying cancer formation and how to target them with those drugs."
     
    This work then was successfully translated to the clinic with the help of the NCI and various research partners.  
     
    One, Sulindac, belongs to of the class of non-steroidal anti-inflammatory drugs, with aspirin being a notable member. Sulindac targets the inflammatory pathway. The other, called Eflornithine, homes in on the  polyamine pathway. Driven by growth factors, this pathway is essential in stimulating growth and development in most living organisms.
     
    In his research, which has been continuously funded by the NCI since 1975, Gerner collaborated closely with Meyskens, who was a professor of medicine at the UA College of Medicine before he moved to University of California, Irvine. Both were members of the Arizona Cancer Center. Even as professor emeritus, Gerner still does research in his lab at the UA and is an active member of the UA's BIO5 Institute. 
     
    Gerner said his group focused on colon cancer in the 1980s because it was the one frequent type of human cancer for which a substantial amount of genetic information became available, especially with the Human Genome Project.
     
    "Our approach strictly focuses on the biological mechanisms and the genetics," Gerner said. "I came to the UA in 1974 and initially worked in cancer therapeutics. By the mid 1980s, I was discouraged by the lack of progress that was being made at the time. So we set out to understand the underlying processes that lead to cancer, such as the roles of various growth factors and cancer-promoting genes. 
     
    According to Jacob, the company's current focus is on intervening with patients facing elevated risk, including cancer survivors or individuals with a genetic predisposition, with the ultimate goal of expand the same approach to other forms of cancer and the general at-risk population. 
     
    Gerner said that many experts estimate at least 70 percent of colorectal cancer are associated with risk factors such as weight gain and a diet high in fat and beef but low in fiber. 
     
    "However, there are a substantial number of individuals who eat perfect diets and exercise, but still face a risk from mutations that arise spontaneously or they inherited," he said. 
     
    "Our drugs are targeting growth and inflammatory pathways leading to the synthesis of polyamines, but diets contain polyamines also. Our company is looking at ways to manage overall risk, including diet, genetic factors and exercise."
     
    In other clinical trials, CPP is also testing the therapy on people with known genetic predispositions to colorectal cancer such as patients with Familial Adenomatous Polyposis, a genetic disease that comes with a nearly 100 percent risk of developing colon cancer before age 40. 
     
    "The only option for most people with FAP is to remove the entire colon in their late teens or early twenties," Gerner said, "and they still face a lifetime of surgeries to control the condition."
     
    Neuroblastoma, a pediatric cancer and the second leading killer of children with cancer, according to Jacob, is another avenue the company is pursuing in a clinical trial. 
     
    In addition to drug therapies, CPP is considering partnerships with food companies to develop certain types of "functional foods" or "medical foods" that would exploit the same science to reduce cancer risk in certain demographics. The company is also developing new diagnostic approaches to identify people who are at higher risk for cancer who could ultimately benefit from specific therapies or medical foods. 
     
    "Part of our ability to reduce risk is having means to assess that risk and evaluate the effectiveness of drugs we are using," Gerner added. "For example, some drugs work better in some people than in others. The goal is to develop diagnostics that tell us about an individual's susceptibility."
     
    David Alberts, director of the UA's Arizona Cancer Center, said: "Gene Gerner and Frank Meyskens, both absolutely brilliant scientists, have transformed exciting laboratory research findings into medications that have the great potential of saving hundreds of thousands of lives. We are very proud that the University of Arizona Cancer Center served as the incubator for this powerful, new chemoprevention technology for colorectal cancer and treatment for recurrent neuroblastoma."
     

    1 image

  13. article Building project tips to ensure a successful and smooth build

    Thursday, April 18, 2013 10:00 pm

    (BPT) - Joey Logano, driver of the No. 22 Shell-Pennzoil Ford Fusion, recently started a huge project: building a race shop for his cars and equipment from the ground up. After deciding to build his own shop, Logano purchased a piece of land and started digging. The massive undertaking brought with it its own trials and learnings, but in the end, Logano took measures to build safely and securely. The project resulted in an impressive race shop that will be used for years to come.

    1 image

  14. article Seven Tips to Make Home Painting Projects Easier

    Wednesday, April 10, 2013 10:00 pm

    (StatePoint) Painting your home yourself? Don’t be intimidated.

    1 image

  15. article Disappointed in LaWall

    Wednesday, April 10, 2013 4:00 am

    I was disappointed in Pima County District Attorney Barbara LaWall’s lack of interest in righting a more than 40-year wrong recently.

    1 image

  16. article Supplement Your Health With Curcumin

    Thursday, April 4, 2013 4:44 am

    (NAPSI)—It could be a healthy idea to take a new look at an old spice.

    1 image

  17. article Coping With Colic

    Thursday, April 4, 2013 4:44 am

    (NAPSI)—If you ever find yourself walking the floor with a colicky baby, heres something you may find comforting: Youre not alone.

    1 image

  18. article County attorney announces April as Month of Awareness and Action to aid victims crime

    Thursday, March 28, 2013 10:35 am

    Pima County Attorney Barbara LaWall encourages the community to participate this April in the many different outreach and educational activities that support victims of crime and promote efforts to prevent violence.

    1 image

  19. article A Mother's Heartfelt Account of Managing High Blood Pressure

    Tuesday, March 26, 2013 10:00 pm

    (BPT) - When Latoya, a writer, administrative accounting assistant, wife and mother of six, was diagnosed with hypertension, she was surprised. “I thought high blood pressure is something only the elderly get,” reflects Latoya. “I didn’t know hypertension may lead to heart attack and stroke."

    1 image

  20. article What's Up UA? - UA Surgeon Works to Revolutionize Organ Transplantation

    Sunday, March 24, 2013 8:35 pm

    What if you could take a damaged lung from a deceased patient, clean it up and refurbish it for someone in need of a transplant? Or what if you could print someone a brand new human lung using a 3-D bioprinter?

    1 image

  21. article A New Approach To Autism

    Thursday, March 21, 2013 4:44 am

    (NAPSI)—Many families may be relieved to learn about a new opportunity to try to stem the tide of autism.

    1 image

  22. article Tough lessons in tough times

    Wednesday, March 20, 2013 4:00 am

    On Sunday, an unusual day for a court to be held in Ohio, a judge found two high school football players guilty of rape. In what became a short trial that divided the football-crazed Rust Belt town of Steubenville, Trent Mays, 17, and Ma’lik Richmond, 16, were found guilty of raping a drunk 16-year-old girl.

    1 image

  23. article New Insight on Slimming Down the Healthy Way

    Tuesday, March 19, 2013 12:27 pm

    (NewsUSA) - According to the ever popular Dr. Oz show on Fox 5, two of the newest ways to shed pounds and maintain a healthy weight are entirely all natural -- green coffee bean extract and raspberry ketone.

    1 image

  24. article Autism Awareness Month gives new insight to children and families

    Sunday, March 17, 2013 10:00 pm

    (BPT) - Each April for the past four decades, National Autism Awareness Month has elevated awareness among the children, parents and friends affected by autism spectrum disorders.

    1 image

  25. article Gov.Brewer announces appointment of Superior Court Clerk in Pima County

    Friday, March 15, 2013 3:10 pm

    Governor Jan Brewer today appointed Toni Hellon to serve as the Clerk of the Superior Court for Pima County.

Next »

Watch Now

youtube

youtube NdNLqb9I0yw

Sunshine School in Oro Valley read more

Sunshine School 9000 N. Oracle Road Tucson, AZ 85704, Suite 204 (520)742-6874 www.sunshineschooltucson.org/

Sunshine School in Oro Valley

Sunshine School 9000 N. Oracle Road Tucson, AZ 85704, Suite 204 (520)742-6874 www.sunshineschoolt...

Northwest Chatter

  • Marana Town Talk: Hot temperatures are here, don’t forget the pool

    Ed Honea, Special to The Explorer

    • icon posted: May 22
  • JTED is a helpful resource for students

    Thelma Grimes, The Explorer

    • icon posted: May 22
  • Such the Spot - The audacious pursuit of dreams

    Darcie Maranich/Special to The Explorer

    • icon Updated: May 19
  • Prime Time Review - 'Kitchen Nightmares' causes chaos for Scottsdale

    Logan Buus/Explorer Intern

    • icon posted: May 19

Featured Videos

youtube

youtube DNRpGy2Miaw

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera read more

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera. A stroller carrying a 14-month-old girl rolled off a slanted train station platform and fell onto the tracks Wednesday, but the girl's mother leaped onto the tracks to rescue her with the help other passengers, transit officials said."What it looks like to us is that the mother became distracted by something, didn't apply the brake on the stroller and the stroller was able to move off the platform and onto the tracks," said Scott Sauer, director of system safety for the Southeastern Pennsylvania Transportation Authority. The accident happened Wednesday afternoon at the 56th Street station of the Market-Frankford Line in west Philadelphia. The platform at the station is slanted slightly for drainage purposes, Sauer said.Surveillance video shows a woman on the eastbound platform with the girl in a jogging stroller, which slowly rolls forward and topples over onto the tracks about 5 feet below. What initially appears to be the girl flying out of the stroller apparently was just a towel or a bag. The stroller comes to rest on the outer rail, which carries no charge. The woman is seen jumping down and lifting the girl to a man waiting on the platform. Other passengers ran to help, and one used an emergency call box to alert SEPTA police, who held an incoming train at the preceding stop.The infant was taken to Children's Hospital of Philadelphia for treatment of a cut on her forehead. Sauer said during a news conference that watching the video was "gut-wrenching.""With the stroller moving at such a slow rate of speed, you know, you want to call out to someone, `Hey, the stroller's moving! Somebody grab the stroller,'" Sauer said. He said the line is one of SEPTA's busiest, with trains running every six to 10 minutes. SEPTA police said no charges will be filed but the accident serves as a reminder for other riders to lock stroller brakes when waiting on platforms.

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera

Baby in stroller Falls Into Train Tracks Mom Jumps In Before Train Barrels In Caught On Camera. A...

Raw:Singing Whitney Houston Fan Kicked Off Flight American Airlines

An American Airlines flight was forced to make an emergency landing after a woman refused to stop...

More Featured Videos

This week's e-Edition

Follow us on Facebook

Sections

  • Home
  • News
  • Business
  • Sports
  • Features
  • Things to Do
  • Opinion
  • Marketplace
  • Blogs
  • Videos
  • Special Sections
  • E-Edition
  • Online Features
  • Weather

Services

  • About Us
  • Contact Us
  • Advertise
  • Subscription Services
  • Newsletter Signup
  • Career Opportunities
  • Submission Forms
  • Site Index
  • Add Search Toolbar

Contact us

explorernews.com

Explorer News
Phone number: 520-797-4384
E-mail: editor@explorernews.com
Address: 7225 N. Mona Lisa Road, #125
Tucson, AZ 85741

Search









© Copyright 2013, The Explorer, Tucson, AZ. Powered by BLOX Content Management System from TownNews.com. [Terms of Use | Privacy Policy]

Forgot?
Now I remember!

Or, use your linked account:

Need an account? Create one now.